Released on the 2010 album Light Me Up, "My Medicine" stands as a defining track in The Pretty Reckless's early career, showcasing the band's signature blend of rock energy and emotional vulnerability. The song features lead vocalist Elizabeth Hurlman's powerful vocals, which anchor the track within the alternative rock genre while delivering a message of self-reliance and healing. As a key component of their discography from that era, the recording captures the band's transition from a cover band to a force in the modern rock scene. The track remains a staple of their live performances, reflecting the themes of resilience and personal strength that permeate their broader body of work.